Article
Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress.
Antioxidants & redox signaling - 20 Apr 2013
Colaianna Marilena, Schiavone Stefania, Zotti Margherita, Tucci Paolo, Morgese Maria Grazia, Bäckdahl Liselotte, Holmdahl Rikard, Krause Karl-Heinz, Cuomo Vincenzo, Trabace Luigia
Abstract excerpt
AIMS: Psychosocial stress alters the hypothalamic-pituitary-adrenal axis (HPA-axis). Increasing evidence shows a link between these alterations and oxidant elevation. Oxidative stress is implicated in the stress response and in the pathogenesis of neurologic and psychiatric diseases. NADPH oxidases (NOXs) are a major source of reactive oxygen species (ROS) in the central nervous system. Here, we investigated the...
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