Article
Social isolation exacerbates schizophrenia-like phenotypes via oxidative stress in cortical interneurons.
Biological psychiatry - 15 May 2013
Jiang Zhihong, Rompala Gregory R, Zhang Shuqin, Cowell Rita M, Nakazawa Kazu
Abstract excerpt
BACKGROUND: Our previous studies indicated that N-methyl-D-aspartate receptor (NMDAR) deletion from a subset of corticolimbic interneurons in the mouse brain during early postnatal development is sufficient to trigger several behavioral and pathophysiological features resembling the symptoms of h...
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