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Article

Delaying reverse transcription does not increase sensitivity of HIV-1 to human TRIM5α.

PloS one - 1 Jan 2013

Battivelli Emilie, Lecossier Denise, Clavel François, Hance Allan J

Abstract excerpt

BACKGROUND: Because uncoating of the capsid is linked to reverse transcription, modifications that delay this process lead to the persistence in the cytoplasm of capsids susceptible to recognition by the human restriction factor TRIM5α (hTRIM5α). It is unknown, however, if increasing the time ava...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23320071
DOI: 10.1371/journal.pone.0052434
PMCID: PMC3540060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23320071-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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