Article
The long rather than the short allele of 5-HTTLPR predisposes Han Chinese to anxiety and reduced connectivity between prefrontal cortex and amygdala.
Neuroscience bulletin - 1 Feb 2013
Long Haixia, Liu Bing, Hou Bing, Wang Chao, Li Jin, Qin Wen, Wang Dawei, Zhou Yuan, Kendrick Keith M, Yu Chunshui, Jiang Tianzi
Abstract excerpt
The short allele of the serotonin-transporter gene is associated with higher risk for anxiety and depression in Caucasians, but this association is still unclear in Asians. Here, we addressed this issue using behavioral and multi-modal MRI approaches in a large group of healthy Han Chinese participants (n = 233). In contrast to findings in Caucasians, we found that long-allele (L) carriers had higher anxiety...
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