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Article

Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F.

Journal of molecular biology - 12 Apr 2013

Albin John S, Anderson John S, Johnson Jeffrey R, Harjes Elena, Matsuo Hiroshi, Krogan Nevan J, Harris Reuben S

Abstract excerpt

APOBEC3F (A3F) and APOBEC3G (A3G) are DNA cytosine deaminases that potently restrict human immunodeficiency virus type 1 replication when the virus is deprived of its accessory protein Vif (virion infectivity factor). Vif counteracts these restriction factors by recruiting A3F and A3G to an E3 ubiquitin (Ub) ligase complex that mediates their polyubiquitination (polyUb) and proteasomal degradation. While previous...

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Identifiers

PMID: 23318957
DOI: 10.1016/j.jmb.2013.01.010
PMCID: PMC3602375

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F.PMID 23318957Read ↗

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