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Article

The Rak/Frk tyrosine kinase associates with and internalizes the epidermal growth factor receptor.

Oncogene - 16 Jan 2014

Jin L, Craven R J

Abstract excerpt

Src is the founding member of a diverse family of intracellular tyrosine kinases, and Src has a key role in promoting cancer growth, in part, through its association with receptor tyrosine kinases. However, some Src-related proteins have widely divergent physiological roles, and these proteins include the Rak/Frk tyrosine kinase (Frk stands for Fyn-related kinase), which inhibits cancer cell growth and suppresses...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23318459
DOI: 10.1038/onc.2012.589

Genes

EGFR
EGF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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The Rak/Frk tyrosine kinase associates with and internalizes the epidermal growth factor receptor.PMID 23318459Read ↗

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Activation of the EGF Receptor by Ligand Binding and Oncogenic Mutations: The “Rotation Model”Semantic proximity Read ↗

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