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Article

Interactions between EGFR and EphA2 promote tumorigenesis through the action of Ephexin1.

Cell death & disease - 6 Jun 2022

Kim Jeeho, Chang In-Youb, You Ho Jin

Abstract excerpt

The cell signaling factors EGFR, EphA2, and Ephexin1 are associated with lung and colorectal cancer and play an important role in tumorigenesis. Although the respective functional roles of EGFR and EphA2 are well known, interactions between these proteins and a functional role for the complex is not understood. Here, we showed that Ephexin1, EphA2, and EGFR are each expressed at higher levels in lung and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35668076
DOI: 10.1038/s41419-022-04984-6
PMCID: PMC9170705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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