Article
Interleukin-13 gene polymorphism G4257A is associated with atopic dermatitis in Japanese patients.
Journal of dermatological science - 1 Nov 2002
Tsunemi Yuichiro, Saeki Hidehisa, Nakamura Koichiro, Sekiya Takashi, Hirai Koichi, Kakinuma Takashi, Fujita Hideki, Asano Noriko, Tanida Yuka, Wakugawa Motoshi, Torii Hideshi, Tamaki Kunihiko
Abstract excerpt
Interleukin (IL)-13 plays an important role in the induction of immunoglobulin E (IgE) and in the pathogenesis of atopic dermatitis (AD). We investigated the allele and genotype frequencies of three IL-13 single nucleotide polymorphisms (SNPs) (A704C and C1103T in the promoter region and G4257A i...
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