Article
Single nucleotide polymorphism in the promoter of the human interleukin-13 gene is associated with asthma in Malaysian adults.
BioMed research international - 1 Jan 2013
Radhakrishnan Ammu Kutty, Raj Vijaya Lechimi, Tan Lee-Keng, Liam Chong-Kin
Abstract excerpt
Asthma susceptibility genes are mapped to a region on human chromosome 5q31-q33, which contains a cluster of proinflammatory cytokine genes such as interleukin-13 (IL-13), which is associated with asthma. This study investigated the allele frequencies of two single nucleotide polymorphisms (SNPs) (-1111C>T and 4257C>A) in the IL-13 gene between asthmatics and healthy volunteers as well as the relationship between...
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