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Article

A single nucleotide polymorphism in the p27(Kip1) gene is associated with primary patency of lower extremity vein bypass grafts.

Journal of vascular surgery - 1 May 2013

Conte Michael S, Owens Christopher D, Belkin Michael, Creager Mark A, Edwards Karen L, Gasper Warren J, Kenagy Richard D, LeBoeuf Renee C, Sobel Michael, Clowes Alexander

Abstract excerpt

OBJECTIVE: Factors responsible for the variability in outcomes after lower extremity vein bypass grafting (LEVBG) are poorly understood. Recent evidence has suggested that a single nucleotide polymorphism (SNP) in the promoter region of the p27(Kip1) gene, a cell-cycle regulator, is associated with coronary in-stent restenosis. We hypothesized an association with vein graft patency. METHODS: This was a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23312942
DOI: 10.1016/j.jvs.2012.11.040
PMCID: PMC3644510

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