Article
Role of Kozak sequence polymorphism of platelet glycoprotein Ibalpha as a risk factor for coronary artery disease and catheter interventions.
Journal of the American College of Cardiology - 1 Oct 2001
Meisel C, Afshar-Kharghan V, Cascorbi I, Laule M, Stangl V, Felix S B, Baumann G, López J A, Roots I, Stangl K
Abstract excerpt
OBJECTIVES: We sought to determine the role of the -5T/C polymorphism of the platelet glycoprotein (GP) Ibalpha as a potential risk factor for coronary artery disease (CAD) and adverse events complicating a coronary catheter intervention. BACKGROUND: The platelet GP Ib-IX-V receptor complex plays a crucial role in arterial thrombus formation. The -5T/C polymorphism of GP Ibalpha is associated with increased...
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