Article
Can screening for genetic markers improve peripheral artery bypass patency?
Journal of vascular surgery - 1 Dec 2002
Kibbe Melina R, Hassett Andrea L Cortese, McSherry Frances, Conner Philip, Bontempo Franklin A, Williford William, Johnson Willard, Makaroun Michel S
Abstract excerpt
OBJECTIVE: Three genetic mutations have been associated with an increased risk of thromboembolic events: factor V Leiden R506Q, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T (MTHFR) mutations. The aim of this study was to determine the effect of these mutations on patency of peripheral bypass procedures and preoperative and postoperative thromboembolic events. METHODS: Two hundred forty-four...
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