Genetic risk factors for hypertrophic scar development.

doi:10.1097/BCR.0b013e3182a2aa41

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Article

Genetic risk factors for hypertrophic scar development.

Journal of burn care & research : official publication of the American Burn Association - 1 Jan 2000

Thompson Callie M, Hocking Anne M, Honari Shari, Muffley Lara A, Ga Maricar, Gibran Nicole S

Abstract excerpt

Hypertrophic scars (HTSs) occur in 30 to 72% patients after thermal injury. Risk factors include skin color, female sex, young age, burn site, and burn severity. Recent correlations between genetic variations and clinical conditions suggest that single-nucleotide polymorphisms (SNPs) may be associated with HTS formation. The authors hypothesized that an SNP in the p27 gene (rs36228499) previously associated with...

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PMID: 23966119
DOI: 10.1097/BCR.0b013e3182a2aa41
PMCID: PMC3786175

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