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Article

P27 and P53 gene polymorphisms and restenosis following coronary implantation of drug-eluting stents.

Cardiology - 1 Jan 2009

Tiroch K, Koch W, Mehilli J, Bottiger C, Schomig A, Kastrati A

Abstract excerpt

OBJECTIVE: Drug-eluting stents (DES) have reduced restenosis rates compared with bare-metal stents. P27 and P53 play important roles in the signal transduction leading to neointimal growth inhibition and induction of apoptosis of smooth muscle cells due to rapamycin and paclitaxel. We hypothesized that genetic variants of P27 and P53 influence the development of restenosis and the clinical outcome of patients...

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Share to Angioplasty, Balloon, Coronary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p27

Share to Polymorphism, Genetic

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Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 18758183
DOI: 10.1159/000151695

Genes

DES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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