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Genetic analysis of haptoglobin polymorphisms with cardiovascular disease and type 2 diabetes in the Diabetes Heart Study.

Cardiovascular diabetology - 11 Feb 2013

Adams Jeremy N, Cox Amanda J, Freedman Barry I, Langefeld Carl D, Carr J Jeffrey, Bowden Donald W

Abstract excerpt

BACKGROUND: Haptoglobin (HP) is an acute phase protein that binds to freely circulating hemoglobin. HP exists as two distinct forms, HP1 and HP2. The longer HP2 form has been associated with cardiovascular (CVD) events and mortality in individuals with type 2 diabetes (T2DM). METHODS: This study examined the association of HP genotypes with subclinical CVD, T2DM risk, and associated risk factors in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23399657
DOI: 10.1186/1475-2840-12-31
PMCID: PMC3576297

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