Article
Differential impact of sickle cell trait on symptomatic and asymptomatic malaria.
Mathematical biosciences and engineering : MBE - 1 Oct 2012
Shim Eunha, Feng Zhilan, Castillo-Chavez Carlos
Abstract excerpt
Individuals who carry the sickle cell trait (S-gene) have a greatly reduced risk of experiencing symptomatic malaria infections. However, previous studies suggest that the sickle cell trait does not protect against acquiring asymptomatic malaria infections, although the proportion of symptomatic infections is up to 50% in areas where malaria is endemic. To examine the differential impact of the sickle cell trait...
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