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Article

A significant effect of the TSPY1 copy number on spermatogenesis efficiency and the phenotypic expression of the gr/gr deletion.

Human molecular genetics - 15 Apr 2013

Shen Ying, Yan Yuanlong, Liu Yunqiang, Zhang Sizhong, Yang Dong, Zhang Peng, Li Lei, Wang Yan, Ma Yongxin, Tao Dachang, Yang Yuan

Abstract excerpt

AZFc deletions cause a significant phenotypic heterogeneity with respect to spermatogenesis; however, the reason for this is poorly understood. Recently, testis-specific protein Y-encoded 1 (TSPY1) copy number variation (CNV) was determined to be a potential genetic modifier of spermatogenesis. We performed a large-scale cohort study to investigate the effect of TSPY1 CNV on spermatogenesis and to elucidate the...

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Source

Identifiers

PMID: 23307928
DOI: 10.1093/hmg/ddt004

Genes

TSPY1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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