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Article

Novel Mutations of TSPY1 Gene Associate Spermatogenic Failure Among Men.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Apr 2022

Paladhi Pranab, Dutta Saurav, Pal Samudra, Bose Gunja, Ghosh Papiya, Chattopadhyay Ratna, Chakravarty Baidyanath, Saha Indranil, Ghosh Sujay

Abstract excerpt

Etiology of male infertility is intriguing owing to complex genetic regulation of human spermatogenesis and ethnic variations in genetic architecture of human populations. The present study characterizes the role of Y chromosome specific spermatogenic regulator testis-specific protein Y-encoded 1 (TSPY1) gene mutation in spermatogenic failure. This case-control study includes 163 cases of spermatogenic failure...

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Identifiers

PMID: 35041134
DOI: 10.1007/s43032-021-00839-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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