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Partial deletions in the AZFc region of the Y chromosome occur in men with impaired as well as normal spermatogenesis

22 Oct 2004

Abstract excerpt

BACKGROUND: Partial deletions of the AZFc region of the Y chromosome were reported to be a significant risk factor for oligo-/azoospermia. In this study, we assessed the occurrence and frequency of partial AZFc microdeletions in patients with spermatogenic failure and in controls with normal spermatogenesis. METHODS: In a retrospective study design, gr/gr, b1/b3 and b2/b3 deletions were analysed by multiplex PCR...

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Identifiers

PMID: 15498781
DOI: 10.1093/humrep/deh558

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Related research

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Partial deletions in the AZFc region of the Y chromosome occur in men with impaired as well as normal spermatogenesisPMID 15498781Read ↗

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Partial deletions are associated with an increased risk of complete deletion in AZFc: a new insight into the role of partial AZFc deletions in male infertilitySemantic proximity Read ↗

The Association of Partial Azoospermia Factor C Deletions and Male Infertility in Northwestern ChinaSemantic proximity Read ↗

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Gene copy number alterations in the azoospermia-associated AZFc region and their effect on spermatogenic impairmentSemantic proximity Read ↗

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