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Article

Isolation of Salmonella mutants resistant to the inhibitory effect of Salicylidene acylhydrazides on flagella-mediated motility.

PloS one - 1 Jan 2013

Martinez-Argudo Isabel, Veenendaal Andreas K J, Liu Xia, Roehrich A Dorothea, Ronessen Maria C, Franzoni Giulia, van Rietschoten Katerine N, Morimoto Yusuke V, Saijo-Hamano Yumiko, Avison Matthew B, Studholme David J, Namba Keiichi, Minamino Tohru, Blocker Ariel J

Abstract excerpt

Salicylidene acylhydrazides identified as inhibitors of virulence-mediating type III secretion systems (T3SSs) potentially target their inner membrane export apparatus. They also lead to inhibition of flagellar T3SS-mediated swimming motility in Salmonella enterica serovar. Typhimurium. We show that INP0404 and INP0405 act by reducing the number of flagella/cell. These molecules still inhibit motility of a...

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Identifiers

PMID: 23300965
DOI: 10.1371/journal.pone.0052179
PMCID: PMC3534715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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