Article
Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with decreased risk for basal cell carcinoma.
Archives of dermatological research - 1 May 2013
Yapijakis Christos, Koronellos Nikolas, Spyridonidou Sofia, Vylliotis Antonis, Avgoustidis Dimitris, Goutas Nikolaos, Vlachodimitropoulos Dimitris, Vairaktaris Eleftherios
Abstract excerpt
The incidence of basal cell carcinoma (BCC) is significantly reduced in individuals treated with inhibitors of angiotensin I-converting enzyme (ACE) that produces angiotensin II. The objective of this study was to investigate the possible association of a functional polymorphism in the ACE gene, which affects its transcription, with risk for BCC. In DNA samples of 92 patients with BCC and 103 healthy controls of...
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