Article
Angiotensinogen, Angiotensin-Converting Enzyme, and Chymase Gene Polymorphisms as Biomarkers for Basal Cell Carcinoma Susceptibility.
Advances in experimental medicine and biology - 1 Jan 2023
Yapijakis Christos, Gintoni Iphigenia, Charalampidou Sevastiana, Angelopoulou Antonia, Papakosta Veronica, Vassiliou Stavros, Chrousos George P
Abstract excerpt
INTRODUCTION: The intake of angiotensin-converting enzyme (ACE) inhibitors and specific antagonists of angiotensin II receptors, widely used as antihypertensive drugs, significantly reduces the risk of developing basal cell carcinoma (BCC), highlighting the possible tumorigenic role of angiotensin II (AngII). We present here the investigated genetic association between the development of BCC and functional DNA...
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