Article
Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with increased risk for oral cancer.
Acta oncologica (Stockholm, Sweden) - 1 Jan 2007
Vairaktaris Eleftherios, Yapijakis Christos, Tsigris Christos, Vassiliou Stavros, Derka Spyridoula, Nkenke Emeka, Spyridonidou Sofia, Vylliotis Antonis, Vorris Eleni, Ragos Vasilis, Neukam Friedrich W, Patsouris Efstratios
Abstract excerpt
INTRODUCTION: In light to recently found contribution of factors associated with thrombosis and inflammation to carcinogenesis, we investigated the possible association of angiotensin I- converting enzyme (ACE) with increased risk for oral cancer. MATERIALS AND METHODS: In DNA samples of 160 patients with oral squamous cell carcinoma and 153 healthy controls of comparable ethnicity, age and sex, we studied the...
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