Article
Association between the angiotensin-converting enzyme (insertion/deletion) and angiotensin II type 1 receptor (A1166C) polymorphisms and breast cancer among Brazilian women.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Mar 2009
Alves Corrêa Silvana Aparecida, Ribeiro de Noronha Samuel Marcos, Nogueira-de-Souza Naiara Correa, Valleta de Carvalho Cristina, Massad Costa Ana Maria, Juvenal Linhares José, Vieira Gomes Mariano Tamura, Guerreiro da Silva Ismael Dale Cotrim
Abstract excerpt
INTRODUCTION: We evaluated the association between components of the renin-angiotensin system and the development of breast cancer in a case-control study by means of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) and angiotensin II type 1 (AT( 1))-receptor A1166C polymorphisms. METHODS: Genotyping was performed by PCR-RFLP (restriction fragment length polymorphism) or PCR (polymerase chain...
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