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Article

Comparative analysis of viral genomes from acute and chronic hepatitis B reveals novel variants associated with a lower rate of chronicity.

Journal of medical virology - 1 Mar 2013

Chook Jack Bee, Ngeow Yun Fong, Khang Tsung Fei, Ng Kee Peng, Tiang Yee Peng, Mohamed Rosmawati

Abstract excerpt

Infection with the hepatitis B virus (HBV) may lead to an acute or chronic infection. It is generally accepted that the clinical outcome of infection depends on the balance between host immunity and viral survival strategies. In order to persist, the virus needs to have a high rate of replication and some immune-escape capabilities. Hence, HBVs lacking these properties are likely to be eliminated more rapidly by...

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Identifiers

PMID: 23297244
DOI: 10.1002/jmv.23500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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