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Article

The evolution and clinical impact of hepatitis B virus genome diversity.

Nature reviews. Gastroenterology & hepatology - 1 Oct 2020

Revill Peter A, Tu Thomas, Netter Hans J, Yuen Lilly K W, Locarnini Stephen A, Littlejohn Margaret

Abstract excerpt

The global burden of hepatitis B virus (HBV) is enormous, with 257 million persons chronically infected, resulting in more than 880,000 deaths per year worldwide. HBV exists as nine different genotypes, which differ in disease progression, natural history and response to therapy. HBV is an ancient virus, with the latest reports greatly expanding the host range of the Hepadnaviridae (to include fish and reptiles)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32467580
DOI: 10.1038/s41575-020-0296-6

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