Article
High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta.
BMC genetics - 19 Apr 2010
Daelemans Caroline, Ritchie Matthew E, Smits Guillaume, Abu-Amero Sayeda, Sudbery Ian M, Forrest Matthew S, Campino Susana, Clark Taane G, Stanier Philip, Kwiatkowski Dominic, Deloukas Panos, Dermitzakis Emmanouil T, Tavaré Simon, Moore Gudrun E, Dunham Ian
Abstract excerpt
BACKGROUND: Imprinted genes show expression from one parental allele only and are important for development and behaviour. This extreme mode of allelic imbalance has been described for approximately 56 human genes. Imprinting status is often disrupted in cancer and dysmorphic syndromes. More subt...
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