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Article

The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice.

Genomics - 1 Nov 2006

Arima Takahiro, Yamasaki Katsuhisa, John Rosalind M, Kato Kiyoko, Sakumi Kunihiko, Nakabeppu Yusaku, Wake Norio, Kono Tomohiro

Abstract excerpt

Imprinting centers (IC) can be defined as cis-elements that are recognized in the germ line and are epigenetically modified to bring about the full imprinting program in a somatic cell. Two paternally expressed human genes, HYMAI and PLAGL1 (LOT1/ZAC), are located within human chromosome 6q24. Within this region lies a 1-kb CpG island that is differentially methylated in somatic cells, unmethylated in sperm, and...

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Identifiers

PMID: 16928428
DOI: 10.1016/j.ygeno.2006.07.005

Genes

PLAGL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice.PMID 16928428Read ↗

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