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Article

Genomic Imprinting at the Porcine PLAGL1 Locus and the Orthologous Locus in the Human.

Genes - 8 Apr 2021

Ahn Jinsoo, Hwang In-Sul, Park Mi-Ryung, Hwang Seongsoo, Lee Kichoon

Abstract excerpt

Implementation of genomic imprinting in mammals often results in cis-acting silencing of a gene cluster and monoallelic expression, which are important for mammalian growth and function. Compared with widely documented imprinting status in humans and mice, current understanding of genomic imprinting in pigs is relatively limited. The objectives of this study were to identify DNA methylation status and allelic...

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PMID: 33918057
DOI: 10.3390/genes12040541
PMCID: PMC8069715

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