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Hedgehog pathway inhibitors: a patent review (2009 – present)

8 Jan 2013

Abstract excerpt

INTRODUCTION: The hedgehog (Hh) pathway is a developmental signaling pathway that plays a key role in directing cellular growth and tissue patterning during embryonic development. Dysregulation of Hh signaling has been linked to the development of a variety of human tumors, and numerous drug development programs in both academia and industry are actively exploring inhibitors of the pathway as anti-cancer agents....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23294277
DOI: 10.1517/13543776.2013.757304

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