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Article

The Hedgehog's tale: developing strategies for targeting cancer.

Nature reviews. Cancer - 26 May 2011

Ng Jessica M Y, Curran Tom

Abstract excerpt

Research into basic developmental biology has frequently yielded insights into cancer biology. This is particularly true for the Hedgehog (HH) pathway. Activating mutations in the HH pathway cause a subset of sporadic and familial, skin (basal cell carcinoma) and brain (medulloblastoma) tumours. Furthermore, the growth of many human tumours is supported by HH pathway activity in stromal cells. Naturally occurring...

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Identifiers

PMID: 21614026
DOI: 10.1038/nrc3079
PMCID: PMC3576812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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