Article
VEGFR-2, CXCR-2 and PAR-1 germline polymorphisms as predictors of survival in pancreatic carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 May 2013
Uzunoglu F G, Kolbe J, Wikman H, Güngör C, Bohn B A, Nentwich M F, Reeh M, König A M, Bockhorn M, Kutup A, Mann O, Izbicki J R, Vashist Y K
Abstract excerpt
BACKGROUND: Hypoxic environment of pancreatic cancer (PC) implicates high vascular in-growth, which may be influenced by angiogenesis-related germline polymorphisms. Our purpose was to evaluate polymorphisms of vascular endothelial growth factor receptor 2 (VEGFR-2), CXC chemokine receptor 2 (CXCR-2), proteinase-activated receptor 1 (PAR-1) and endostatin (ES) as prognostic markers for disease-free (DFS) and...
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