Article
Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk.
International journal of cancer - 1 Apr 2018
Duan Bensong, Hu Jiangfeng, Liu Hongliang, Wang Yanru, Li Hongyu, Liu Shun, Xie Jichun, Owzar Kouros, Abbruzzese James, Hurwitz Herbert, Gao Hengjun, Wei Qingyi
Abstract excerpt
The platelet-derived growth factor (PDGF) signaling pathway plays important roles in development and progression of human cancers. In our study, we aimed to identify genetic variants of the PDGF pathway genes associated with pancreatic cancer (PC) risk in European populations using three published genome-wide association study datasets, which consisted of 9,381 cases and 7,719 controls. The expression...
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