Article
Impact of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) single nucleotide polymorphisms on outcome in gastroenteropancreatic neuroendocrine neoplasms.
PloS one - 1 Jan 2018
Berardi Rossana, Torniai Mariangela, Partelli Stefano, Rubini Corrado, Pagliaretta Silvia, Savini Agnese, Polenta Vanessa, Santoni Matteo, Giampieri Riccardo, Onorati Sofia, Barucca Federica, Murrone Alberto, Bianchi Francesca, Falconi Massimo
Abstract excerpt
Angiogenesis represents a key event in cancer development, leading to local invasion e metastatization, and might be considered a basic feature in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) with a high expression of angiogenic molecules. We aimed to analyze the prognostic and predictive role of angiogenic factors in GEP-NENs through the analysis of single nucleotide polymorphisms (SNPs) of VEGF-A,...
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