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Article

C-X-C motif receptor 2, endostatin and proteinase-activated receptor 1 polymorphisms as prognostic factors in NSCLC.

Lung cancer (Amsterdam, Netherlands) - 1 Jul 2013

Uzunoglu Faik Güntac, Yavari Neda, Bohn Benjamin Alexander, Nentwich Michael Fabian, Reeh Matthias, Pantel Klaus, Perez Daniel, Tsui Tung Yu, Bockhorn Maximilian, Mann Oliver, Izbicki Jakob Robert, Wikman Harriet, Vashist Yogesh Kumar

Abstract excerpt

The progress of non-small cell lung cancer (NSCLC) is dependent on sufficient angiogenesis. Thrombin induced activation of proteinase-activated receptor 1 (PAR-1) on platelets leads to platelet secretion and aggregation. This influences cell survival, apoptosis and angiogenesis by the release of...

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Identifiers

PMID: 23548249
DOI: 10.1016/j.lungcan.2013.03.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23548249-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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