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Article

Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo

15 Sept 2015

Abstract excerpt

Aristolochic acid (AA) is a carcinogenic, mutagenic and nephrotoxic compound commonly isolated from members of the plant family of Aristolochiaceae (such as Aristolochia and Asarum) and used in Chinese herbal medicine. Use of AA and AA‑containing plants causes chronic kidney disease (CKD) and upper urinary tract carcinoma (UUC); however, the underlying mechanism remains to be defined. miRNAs regulate a number of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26397152
DOI: 10.3892/mmr.2015.4330

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