Article
Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk.
Carcinogenesis - 1 Apr 2013
Liu Hongliang, Wang Li-E, Liu Zhensheng, Chen Wei V, Amos Christopher I, Lee Jeffrey E, Iles Mark M, Law Matthew H, Barrett Jennifer H, Montgomery Grant W, Taylor John C, MacGregor Stuart, Cust Anne E, Newton Bishop Julia A, Hayward Nicholas K, Bishop D Timothy, Mann Graham J, Affleck Paul, Wei Qingyi
Abstract excerpt
Genome-wide association studies (GWASs) have mainly focused on top significant single nucleotide polymorphisms (SNPs), most of which did not have clear biological functions but were just surrogates for unknown causal variants. Studying SNPs with modest association and putative functions in biolog...
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