Article
Replication and predictive value of SNPs associated with melanoma and pigmentation traits in a Southern European case-control study.
PloS one - 1 Jan 2013
Stefanaki Irene, Panagiotou Orestis A, Kodela Elisavet, Gogas Helen, Kypreou Katerina P, Chatzinasiou Foteini, Nikolaou Vasiliki, Plaka Michaela, Kalfa Iro, Antoniou Christina, Ioannidis John P A, Evangelou Evangelos, Stratigos Alexander J
Abstract excerpt
BACKGROUND: Genetic association studies have revealed numerous polymorphisms conferring susceptibility to melanoma. We aimed to replicate previously discovered melanoma-associated single-nucleotide polymorphisms (SNPs) in a Greek case-control population, and examine their predictive value. METHODS: Based on a field synopsis of genetic variants of melanoma (MelGene), we genotyped 284 patients and 284 controls at...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Case-Control Studies
- Female
- Humans
- Male
- Melanoma
- Middle Aged