Article
Association between maternal and fetal TLR4 (896A>G, 1196C>T) gene polymorphisms and the risk of pre-term birth in the Polish population.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Mar 2013
Bitner Adam, Sobala Wojciech, Kalinka Jarosław
Abstract excerpt
PROBLEM: Bacteria activates Toll-like receptor 4 on immune system cells leading to preterm birth (PTB). The aim of study was to evaluate the impact of maternal and fetal carriage of TLR4 gene polymorphisms on the risk of PTB. METHOD OF STUDY: Frequency of TLR4 (896A>G, 1196C>T) variants was determined in 121 women who delivered preterm, 152 women who delivered at term, 49 term newborns and 35 preterm newborns...
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