Article
Impact of TLR7 and TLR9 polymorphisms on susceptibility to placental infections and pregnancy complications.
Journal of reproductive immunology - 1 Aug 2021
Sánchez-Luquez Karen, Schadock Ines Claudia, Gonçalves Carla Vitola, Tornatore Michele, Finger-Jardim Fabiana, Avila Emiliana Claro, Soares Marcelo Alves, de Martínez Ana Maria Barral, Ellwanger Joel Henrique, Chies José Artur Bogo, da Hora Vanusa Pousada
Abstract excerpt
This study evaluated the impact of the TLR7 Gln11Leu (rs179008) and TLR9 -1237 T/C (rs5743836) single nucleotide polymorphisms (SNPs) on susceptibility to placental infections and pregnancy complications in 455 Brazilian women. Demographic, socioeconomic, gynecological, and clinical characteristics of the women were collected. Placental tissues were sampled from pregnant women and human and viral DNA was...
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