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Article

A mechanistic model of early FcεRI signaling: lipid rafts and the question of protection from dephosphorylation.

PloS one - 1 Jan 2012

Barua Dipak, Goldstein Byron

Abstract excerpt

We present a model of the early events in mast cell signaling mediated by FcεRI where the plasma membrane is composed of many small ordered lipid domains (rafts), surrounded by a non-order region of lipids consisting of the remaining plasma membrane. The model treats the rafts as transient structures that constantly form and breakup, but that maintain a fixed average number per cell. The rafts have a high...

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Identifiers

PMID: 23284735
DOI: 10.1371/journal.pone.0051669
PMCID: PMC3524258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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