Article
High GINS2 transcript level predicts poor prognosis and correlates with high histological grade and endocrine therapy resistance through mammary cancer stem cells in breast cancer patients.
Breast cancer research and treatment - 1 Nov 2014
Zheng Ming, Zhou Yinghui, Yang Xiangmin, Tang Juan, Wei Ding, Zhang Yang, Jiang Jian-Li, Chen Zhi-Nan, Zhu Ping
Abstract excerpt
GINS2, a subunit of the GINS complex, is overexpressed in lung adenocarcinoma and metastatic breast tumor; however, its prognostic power and possible molecular mechanisms in breast cancer (BC) remain unclear. In this study, we aimed to explore the function of GINS2 in BC. The association between GINS2 transcript level and the clinical outcome of BC patients were estimated using Kaplan-Meier plots, multivariate...
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