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Article

A TRPV channel modulates C. elegans neurosecretion, larval starvation survival, and adult lifespan.

PLoS genetics - 1 Oct 2008

Lee Brian H, Ashrafi Kaveh

Abstract excerpt

For most organisms, food is only intermittently available; therefore, molecular mechanisms that couple sensation of nutrient availability to growth and development are critical for survival. These mechanisms, however, remain poorly defined. In the absence of nutrients, newly hatched first larval (L1) stage Caenorhabditis elegans halt development and survive in this state for several weeks. We isolated mutations...

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PMID: 18846209
DOI: 10.1371/journal.pgen.1000213
PMCID: PMC2556084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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