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Article

NBS1 rs1805794G>C polymorphism is associated with decreased risk of acute myeloid leukemia in a Chinese population.

Molecular biology reports - 1 May 2013

Li Na, Xu Yanzhe, Zheng Jian, Jiang Lan, You Yonghe, Wu Hongchun, Li Wei, Wu Depei, Zhou Yifeng

Abstract excerpt

As a key encoding protein gene of MRN (MRE11-RAD50-NBS1) complex, NBS1 plays a crucial role in maintaining genomic stability and preventing cell apoptosis, inflammation and tumorgenesis. Single nucleotide polymorphisms (rs2735383 and rs1805794) in NBS1 have been frequently studied in some cancers with discordant results in previous case-control studies. However, the relationship between these two functional...

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Source

Identifiers

PMID: 23283743
DOI: 10.1007/s11033-012-2451-9

Genes

MRE11
RAD50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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