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Article

Mapping Hfq-RNA interaction surfaces using tryptophan fluorescence quenching.

Nucleic acids research - 1 Feb 2014

Robinson Kirsten E, Orans Jillian, Kovach Alexander R, Link Todd M, Brennan Richard G

Abstract excerpt

Hfq is a posttranscriptional riboregulator and RNA chaperone that binds small RNAs and target mRNAs to effect their annealing and message-specific regulation in response to environmental stressors. Structures of Hfq-RNA complexes indicate that U-rich sequences prefer the proximal face and A-rich sequences the distal face; however, the Hfq-binding sites of most RNAs are unknown. Here, we present an Hfq-RNA mapping...

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Identifiers

PMID: 24288369
DOI: 10.1093/nar/gkt1171
PMCID: PMC3936774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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