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Article

Schizophrenia endophenotypes as treatment targets.

Expert opinion on therapeutic targets - 1 Sept 2007

Thaker Gunvant K

Abstract excerpt

Schizophrenia is a complex disorder that encompasses several clinical symptom domains and functional impairments. Existing treatments are meager, effective only against positive symptoms without benefiting negative symptoms and functional impairments. The drug discovery process has focused mostly on targeting D2 dopamine receptors. This followed the serendipitous discovery of the antipsychotic effects of...

Topics

Animals
Antipsychotic Agents
Brain
Drug Design
Eye
Humans
Phenotype
Reflex, Startle
Schizophrenia

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 17845145
DOI: 10.1517/14728222.11.9.1189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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