Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder.

Schizophrenia bulletin - 1 Jan 2007

Braff David L, Freedman Robert, Schork Nicholas J, Gottesman Irving I

Abstract excerpt

The genetics of schizophrenia has been approached utilizing a variety of methods. One emerging strategy is the use of endophenotypes in order to understand and identify the functional importance of genetically transmitted, brain-based deficits across schizophrenia kindreds. The endophenotype strategy is a topic of this issue of Schizophrenia Bulletin. Endophenotypes are quantitative, heritable, trait-related...

Topics

Antipsychotic Agents
Brain
Genetic Markers
Genetic Predisposition to Disease
Genetic Research
Genetic Variation
Humans
Phenotype
Polymorphism, Single Nucleotide
Schizophrenia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 17088422
DOI: 10.1093/schbul/sbl049
PMCID: PMC2632293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder.PMID 17088422Read ↗

The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration.Semantic proximity Read ↗

The use of neurophysiological endophenotypes to understand the genetic basis of schizophrenia.Semantic proximity Read ↗

Consortium on the Genetics of Schizophrenia (COGS) assessment of endophenotypes for schizophrenia: an introduction to this Special Issue of Schizophrenia Research.Semantic proximity Read ↗

The Consortium on the Genetics of Schizophrenia: neurocognitive endophenotypes.Semantic proximity Read ↗

Endophenotypes in the genetic analyses of mental disorders.Semantic proximity Read ↗

Arguments for the sake of endophenotypes: examining common misconceptions about the use of endophenotypes in psychiatric genetics.Semantic proximity Read ↗

Endophenotypes in schizophrenia: a selective review.Semantic proximity Read ↗

Electrophysiological Endophenotypes for Schizophrenia.Semantic proximity Read ↗

The endophenotype concept in psychiatry: etymology and strategic intentions.Semantic proximity Read ↗

Schizophrenia endophenotypes as treatment targets.Semantic proximity Read ↗

Genetic bases for endophenotypes in psychiatric disorders.Semantic proximity Read ↗

Association analysis of 94 candidate genes and schizophrenia-related endophenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.