Article
Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder.
Schizophrenia bulletin - 1 Jan 2007
Braff David L, Freedman Robert, Schork Nicholas J, Gottesman Irving I
Abstract excerpt
The genetics of schizophrenia has been approached utilizing a variety of methods. One emerging strategy is the use of endophenotypes in order to understand and identify the functional importance of genetically transmitted, brain-based deficits across schizophrenia kindreds. The endophenotype strategy is a topic of this issue of Schizophrenia Bulletin. Endophenotypes are quantitative, heritable, trait-related...
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