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Article

Two rare variants explain association with acute myocardial infarction in an extended genomic region including the apolipoprotein(A) gene.

Annals of human genetics - 1 Jan 2013

Koch Werner, Mueller Jakob C, Schrempf Matthias, Wolferstetter Hannah, Kirchhofer Johannes, Schömig Albert, Kastrati Adnan

Abstract excerpt

Relatively low numbers of kringle 4 type 2 repeats in apolipoprotein(a) and specific haplotypes of the SLC22A3-LPAL2-LPA region on chromosome 6 are associated with an increased risk of coronary disease. We examined the possibility that rs3798220 and rs10455872, short variations located in LPA [the apolipoprotein(a) gene], and related to the number of kringle 4 type 2 repeats, may serve as markers for the...

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Source

Identifiers

PMID: 23278389
DOI: 10.1111/j.1469-1809.2012.00739.x

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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