Article
Association of polymorphisms of the apolipoprotein(a) gene with lipoprotein(a) levels and myocardial infarction.
Circulation - 11 Feb 2003
Holmer Stephan R, Hengstenberg Christian, Kraft Hans-Georg, Mayer Björn, Pöll Melanie, Kürzinger Susanne, Fischer Marcus, Löwel Hannelore, Klein Gernot, Riegger Günter A J, Schunkert Heribert
Abstract excerpt
BACKGROUND: Serum lipoprotein(a) [Lp(a)] concentration is largely determined by variability at the apolipoprotein(a) gene locus. Most prominent effects relate to polymorphisms in the promoter (a pentanucleotide [PN] repeat) and coding regions (a kringle IV [K4] repeat), the latter of which also a...
Topics
- Apolipoproteins
- Apoprotein(a)
- Female
- Genetic Linkage
- Genotype
- Germany
- Haplotypes
- Humans
- Kringles
- Lipoprotein(a)
- Logistic Models
- Male
- Middle Aged
- Myocardial Infarction
- Odds Ratio