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Article

Association of polymorphisms of the apolipoprotein(a) gene with lipoprotein(a) levels and myocardial infarction.

Circulation - 11 Feb 2003

Holmer Stephan R, Hengstenberg Christian, Kraft Hans-Georg, Mayer Björn, Pöll Melanie, Kürzinger Susanne, Fischer Marcus, Löwel Hannelore, Klein Gernot, Riegger Günter A J, Schunkert Heribert

Abstract excerpt

BACKGROUND: Serum lipoprotein(a) [Lp(a)] concentration is largely determined by variability at the apolipoprotein(a) gene locus. Most prominent effects relate to polymorphisms in the promoter (a pentanucleotide [PN] repeat) and coding regions (a kringle IV [K4] repeat), the latter of which also affects Lp(a) particle size. The impact of these polymorphisms on cardiovascular risk is poorly understood. METHODS AND...

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PMID: 12578871
DOI: 10.1161/01.cir.0000048125.79640.77

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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