Article
Lipoprotein(a) and risk of myocardial infarction--genetic epidemiologic evidence of causality.
Scandinavian journal of clinical and laboratory investigation - 1 Apr 2011
Kamstrup Pia R, Tybjærg-Hansen Anne, Nordestgaard Børge G
Abstract excerpt
Elevated levels of lipoprotein(a) are associated with an increased risk of myocardial infarction. Our study aimed to test whether genetic data are consistent with this association being causal. Accordingly, we developed a high-throughput realtime PCR assay to genotype for the lipoprotein(a) kringle IV type 2 (KIV-2) repeat polymorphism in the LPA gene in > 40,000 individuals. The LPA KIV-2 genotype associated...
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